english
1
general::
Phrase(s): in spite of someone or something without regard to someone or something; even though another course had been prescribed; ignoring a warning. • In spite of her orders to stay, I left. • In spite of the bad weather, I had fun on vacation.
McGrawhill's American Idioms And Phrasal Verbs
2
general::
Regardless of, in defiance of, as in They kept on in spite of their fears. [c. 1400]
American Heritage Idioms