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شوک هیپواسمزی
The hypo-osmotic shock method likely induces a pro-inflammatory M1-like activation state, based on in- creased secretion of IL-1 and IL-6 by the macrophages in vitro [51].
Macrophages activated by hypo-osmotic shock (M1-like; local)
, Activated macrophages for treating skin ulceration: gene expression in human monocytes after hypo-osmotic shock, Clin.
, 1997 • macrophages from blood elderly patients periphery and topically on ulcer macrophages to pressure ulcers of young, healthy donors, • range of sizes (not • 0.05 mL/injection; 1 cm between resulted in healing of 27% of those stimulated by hypo-osmotic shock (n = 72 ulcer indicated) injections along periphery
The results revealed that expression of several genes related to wound healing (IL-1, IL-6, TGF-β, FGF-8, TNF receptors, VEGF, and GM-CSF, to name a few) dramatically increased due to hypo-osmotic shock.
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