1
عمومی::
عروقی مغزی
The changes in extracellular pH and CBF rapidly occur after Paco2 adjustments because CO2 freely diffuses across the cerebrovascular endothelium and the BBB.
Cerebrovascular tone and CBF are therefore under the control of a complex regulatory system (Fig. 11.8).
Rather, cerebral autoregulation should be viewed as a dynamic process and that the mor- phologic form of the autoregulatory curve is the result of the integration of all the variables that affect cerebrovas- cular tone in an interdependent manner.8,23 Therefore, a continuum of vascular responsiveness in both the lower and upper limits and in the plateau probably exists as the ability of the cerebrovascular bed to dilate or constrict is exhausted.
Selection of the target range based on the baseline pres- sure, after due consideration of comorbid conditions that may impact cerebrovascular and cardiovascular per- formance, may be preferable.
In addition, the cerebrovascular effects of volatile anes- thetics are modulated by the simultaneous administra- tion of other CNS-active drugs.
واژگان شبکه مترجمین ایران