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The dorsal retina, however, is not responsive to thyroid hormones and does not generate new neurons.
The dorsal retina appears to be insulated from thyroid hormones by expressing deiodinase III, which degrades the T3 produced by deiodinase II.
DORSAL-VENTRAL AND PROXIMAL-DISTAL AXES The dorsal-ventral axis of the wing is formed at the second instar stage by the expression of the apterous gene in the prospective dorsal cells of the wing disc (Blair 1993; Diaz-Benjumea and Cohen 1993).
The dorsal portion of the wing synthesizes transmembrane proteins that prevent the intermixing of the dorsal and ventral cells (Milan et al. 2005).
At the boundary between the dorsal and ventral compartments, the Apterous and Vestigial transcription factors interact to activate the gene encoding the Wnt paracrine factor Wingless (FIGURE 21.16B).
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