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پستاندار
Mammalian cells, on the other hand, remove some mannose residues from the precursor (trimming) and then sequentially add specific sugars to yield a glycoprotein with an oligo saccharide that terminates in sialic acid.
However, an additional advan tage of using filamentous fungi as hosts for the production of mammalian proteins is their ability to add mammalianlike sugars to proteins.
For this and other rea sons, gene expression systems that use insect or mammalian cells have been developed.
Mammalian Glycosylation and Processing of Proteins in Insect Cells
Although insect cells can process proteins in a manner similar to that of other eukaryotes, some mammalian proteins produced in S. frugiperda cell lines are not authentically glycosylated.
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