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ملانوما
In rare cases, the most serious type of skin cancer (called melanoma) may develop in this type of mole.
Although not common, they tend to be numerous, and they increase a person's risk of melanoma.
Although the genetics of melanoma has been widely studied, much less is known about genes involved in the development of benign moles.
In susceptible individuals (those with fair skin, light hair, skin that burns instead of tans, a family history of melanoma, and genetic risk factors such as deletion of or mutations in the CDKN2A gene), ultraviolet radiation from repeated sun exposure can damage existing moles, increasing their risk of becoming malignant.
Research has shown that individuals who have an abundance of moles are at an increased risk of melanoma.
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