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عمومی::
سوگامادکس
* After injection of the selective binding agent sugammadex, neuromuscular transmission is
restored because of 1:1 binding of sugammadex to rocuronium.
Doses of 0.6 mg/kg have a longer duration in neonates (<1 month) than in infants (5 to 12 months), so a reduced dosage (0.45 mg/kg) is recommended.86 Rocuronium may be used for rapid-sequence induction as succinylcholine is relatively contraindicated because of the possible presence of undiagnosed muscle dystrophy in pediatric patients, especially in boys.34 The use of rocuronium in large doses (1.2 mg/kg) might become widespread in all age groups for rapid-sequence induction if and when the selective binding agent sugammadex becomes available (see "Sugammadex").
The monopoly occupied by anticholinesterase agents might be challenged soon with the introduction of a selective binding agent, sugammadex, which is now undergoing clinical trials in North America and Europe.
Sugammadex
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