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وکورونیوم
However, neuromuscular blocking agents were found to make a difference in lower abdominal surgery, where surgical conditions were better in patients receiving vecuronium (Fig. 20-1).6 In addition to providing immobility and better surgical conditions, neuromuscular blocking agents improve intubating conditions.
For example, the ED95 for vecuronium is 0.05 mg/kg, which means that half the patients will achieve at least 95% block of single twitch (compared with the prevecuronium value) with that dose, and half the subjects will reach <95% block.
Therefore, it has one- sixth the potency of vecuronium.
In other words, compared with vecuronium, 6 times as much rocuronium has to be given to produce the same effect.
Pancuronium, vecuronium, cisatracurium, and mivacurium are not as effective as defasciculants.
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