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عمومی::
آنژیوتانسین، آنژیوتانسین
A variety of medica- tions can impact autoregulation, either through modula- tion of sympathetic nervous system activity (�-antagonists, a2-agonists) or by direct reduction of vasomotor tone (cal- cium channel antagonists, nitrates, angiotensin receptor blockers, angiotensin converting enzyme [ACE] inhibitors).
Angiotensin II, Angiotensin-Converting Enzyme Inhibitors, and Angiotensin Receptor Antagonists There has been a renaissance of the use of angiotensin II (AII) for the treatment of vasodilatory shock that is refrac- tory to conventional vasopressor agents.،Increased activity of pro- gesterone results in increased production of nitric oxide and prostacyclin, which together with a decreased response to nor- epinephrine and angiotensin result in vasodilation.
The sensitivity of vascular receptors to angiotensin II is significantly decreased during normal pregnancy.
In preeclamptic patients, hypertension and vasocon- striction are the result of hyperactivity of the angiotensin II receptors.
Spinal anesthesia does not influence the angiotensin system and thus may result in a lesser degree of hypotension in preeclamptic patients than in healthy patients.
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