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زیست شناسی::
باکولوویروس
Baculoviruses are a large, diverse group of doublestranded DNA viruses that specifically infect arthropods, including many insect species, and are not infectious to other animals.
Baculoviruses have been highly successful as delivery systems for introducing target genes for production of high levels of heterologous pro teins in insect cells.
With this system, almost all of the progeny baculoviruses are recombinant.
A large number of biologically active heterologous pro teins have also been produced in insect cells grown in cul ture using baculoviruses to deliver the gene of interest into the insect host cell.
This system is advantageous because posttranslational protein modification is similar in insects and mammals, and the baculoviruses used in these systems do not infect humans or other insect cells.
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