داستان آبیدیک

bioconversion


فارسی

1 شیمی:: تبدیل زیستی

The Rationale Behind the Use of Prodrug Barrier to Overcome Examples of Prodrugs Preferable Site of Bioconversion Common Functional Group Amenable to Prodrug Design Formulation and administration However, the relatively slow and incomplete bioconversion of some simple alkyl esters in human blood can sometimes result in lower than predicted bioavailability. Phosphate pro- drugs typically display excellent or adequate chemical stability and rapid bioconversion to parent drug by phosphatases present at the intestinal brush border or in the liver. Improved physi- cochemical properties and easy bioconversion of N-acyl derivative of 5-fluorouracil enhances the oral and rectal absorption of the parent drug. Antiviral Agent Valacyclovir (Valtrex) L-Valyl ester of acyclovir Bioconversion by valacyclovir hydrolase.

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