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پلاناریا
Planaria lacking a zeta population can be made through zfp-1 RNAi knockdown.
In planaria, Wnt/fl-catenin functions to establish anterior-posterior polarity of the regenerating flat- worm; here, though, Wnts functioning through p-catenm promotes tail development while repressing head regeneration (Gurley et al. 2008; Petersen and Reddien 2008, 2011).
Several labs took a comparative approach to understanding the control over polarity during head regeneration in planaria.
It is interesting that some species of planaria are incapable of regeneration.
When planaria of the species Procotyla fluviatilis and Dendro- coelum lacteum are decapitated, they are unable to regenerate their heads.
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