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زیست شناسی::
پلیهدرین
In this form, the viral nu cleocapsids (virions) are clustered in a matrix that is made up of the pro tein polyhedrin, which protects the virions from degradation in the environment.
Following ingestion, the virus is taken up into the midgut of the insect, the polyhedrin matrix dissolves due to the alkaline gut environment, and the virions enter midgut cells.
This form of the virus, known as the budding form, is not embedded in a polyhedrin matrix and is not infectious to other individual insect hosts, although it can infect cultured insect cells.
During the late stages of the infection cycle in the insect host, about 36 to 48 hours after infection, the polyhedrin protein is produced in mas sive quantities and continues for 4 to 5 days, until the infected cells rupture and the host organism dies.
The promoter for the polyhedrin (polyh) gene is exceptionally strong, and transcription from this promoter can account for as much as 25% of the mRNA produced in cells infected with the virus.
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