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عمومی::
ریمیلیناسیون
Spinal cord Improved remyelination in mice
Finally, systemic M-CSF has been reported to increase macro- phage numbers and improve repair following ischemic kidney injury in mice [68] and promoted remyelination following spinal cord injury in
, Stimulation of monocytes, macrophages, and microglia by amphotericin B and macrophage colo- ny-stimulating factor promotes remyelination, J.
For example, activin-A, a protein that instructs oligodendrocyte differentiation during CNS remyelination, has been recently identified as an important macrophage-derived reparative mediator.
M2 microglia and macrophages drive oligodendrocyte differ- entiation during CNS remyelination.
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