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زیست شناسی::
دگرتمایزی
Here, regeneration occurs through the repatterning of existing tissues (transdifferentiation), and there is little new growth.
EPIMORPHOSIS, COMPENSATION, AND TRANSDIFFERENTIATION: THE HEART OF THE MATTER The zebrafish has a relatively simple tubular heart.
, increase in cell size), but this has yet to be shown to occur in zebrafish heart regeneration The developing zebrafish heart also appears to be capable of morphailaxis or transdifferentiation during regeneration.
These results suggest that, at least during larval development, cardiac myocytes are capable of undergoing transdifferentiation to support regeneration of the heart.
Thus, it appears the cells of the zebrafish heart employ multiple mechanisms to power its regeneration: blastema formation through epimorphosis, compensatory proliferation, and Notch-mediated transdifferentiation.
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