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کشاورزی::
گلوکورونید
Glucuronidation is a common conjugation of an acceptor molecule with a suitable functional group to the anionic form of activated D-glucuronic acid (UDP-glucuronic acid) by UDP-glucuronosyltransferases (Dutton, 1980; Kaivosaari et al.
Glucuronidation occurs with a variety of endogenous and exogenous substrates with diverse functional groups (Miners et al.
It is also noteworthy that glucuronidation was long considered to be solely a detoxification reaction, with the glucuronides being biologically less active than their aglycones (Dutton, 1980; Kroemer and Klotz, 1992; Mulder, 1986, 1992; Mullangi et al.
However, an increasing number of biologically active glucuronides have been described, sometimes with the glucuronides possessing even higher biological activity than their aglycones (Kroemer and Klotz, 1992; Mullangi et al.
The best-known example of this phenomenon is morphine, whereby morphine-6-glucuronide is even more pharmaco- logically active than morphine itself (Kroemer and Klotz, 1992; Mulder, 1992; Ritter, 2000; Zia-Amirhosseini et al.
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