2
عمومی::
ایمنی شناسی، ایمونولوژیک
Immunologic Disorders
Systemic or "whole body" influences such as endocrine function, allergies, and immunologic responses may also affect the larynx, so it is important for the voice pathologist to recognize these medical disorders that may influence voice production.1'3'13,56 To understand the relationship between body systems that affect the larynx, some researchers
Voice disorders seem to occur in per- sons with immunologic disease but without other obvious contributing eti- ologies.3'13'70 Although there are few pub- lished reports of the impact of immuno-،Such immunologic autoreactivity probably results from inflammation and develops as a consequence of chronic local tissue destruction.''1' As endometriosis is associated with an inflammatory response/environment (as discussed below), it is perhaps not surprising that women with endometriosis can exhibit a hypersensitivity to inflammation at sites distant from pelvic implants."1
Macrophages are a key element of the innate immune response, the part of the immune system that is not antigen specific and does not involve immunologic memory.
While it is clear that immunologic abnormalities are a consequence of endometriosis, they certainly also play an important role in its pathogenesis.
• Increased survival of refluxed endometrial cells (resistance to apoptosis), inducing inflammatory and immunologic changes.
14 A wide variety of immunologic abnormalities have been described in women with endometriosis.
واژگان شبکه مترجمین ایران