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عمومی::
متسعکنندگی عروق (وازودیلاتوری)
NO, in particular NO of neuronal origin, is an important although not exclusive mediator of CO2-induced vasodilation.10 The vasodilatory response to hypercapnia is also mediated in part by prostaglandins.
At the same time, sympathetic nerves reduce the vasodilatory capacity of the cerebral vessels during hypotension.
Angiotensin II, Angiotensin-Converting Enzyme Inhibitors, and Angiotensin Receptor Antagonists There has been a renaissance of the use of angiotensin II (AII) for the treatment of vasodilatory shock that is refrac- tory to conventional vasopressor agents.
All volatile anesthetics, in a manner similar to intravenous sedative-hypnotic drugs, suppress cerebral metabolism in a dose-related fashion.129-132 Volatile anesthetics also possess intrinsic cerebral vasodilatory activity as a result of direct effects on vascular smooth muscle.
At 1 MAC, concentrations of isoflurane, sevoflurane, or desflurane, CBF remains unchanged; at this concentration, CMR sup- pression and vasodilatory effects are in balance.
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