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زیست شناسی::
اپیدرم
Within 6-12 hours, epidermal cells from the remaining stump migrate to cover the wound surface, forming the wound epidermis.
In contrast to wound healing in mammals, no scar forms, and the dermis does not move with the epidermis to cover the site of amputation.
During the next four days, the extracellular matrices of the tissues beneath the wound epidermis are degraded by proteases, liberating single cells that undergo dramatic dedifferentiation: bone cells, cartilage cells, fibroblasts, and myocytes all lose their differentiated characteristics.
the wound epidermis thickens to form the apical epidermal cap (AEC) (see Figure 22.17B), which acts similarly to the apical ectodermal ridge during normal limb development (see Chapter 19; Han et al. 2001).
Similarly, GFP-marked muscle cells gave rise only to muscle, and GFP-marked epidermal cells only produced the epidermis of the regenerated limb.
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عمومی::
اپیدرم
Comprised of a dermis and epidermis layer, like all skin.
The deeper of the layers is the dermis, containing capillaries and glands and the epidermis is the layer just below the nail plate and moves towards the fingertip with the nail plate.
Human skin is comprised of 2 main layers, the dermis, and the epidermis.
The epidermis is the top, outermost layer, providing the initial layer of protection.
THE EPIDERMIS
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