Lymphocytes mediate the acquired immune response.
B lymphocytes mature in the bone marrow and secrete immunoglobulins, which are antigen-specific antibodies directed against extracellular microorganisms.
T lymphocytes help B cells to make antibodies and also eliminate intracellular pathogens by activating macrophages and by killing virus-infected or malignant cells.
is a cytokine involved in inflammatory and immune responses and is secreted by activated monocytes and macrophages, T and B lymphocytes, and NK cells.
TNF-a is a cytokine produced by activated lymphocytes, macrophages, and NK cells, among others.
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