1 عمومی:: فارماکوژنومیک، فارماکوژنومیکس
Define pharmacogenetics and pharmacogenomics. A related term, pharmacogenomics, is often used interchangeably but includes the study of the genetic basis of disease and the pharmacological impact of drugs on the disease process (Mancinelli et al, 2000). In this chapter, the term "pharmacogenetics" is interchangeable with "pharmacogenomics." Pharmacogenomic test: An assay intended to study interindividual variations in whole-genome or candidate gene, single-nucleotide polymorphism (SNP) maps, haplotype markers, or alterations in gene expression or inactivation that may be correlated with pharmacological function and therapeutic response. Pharmacogenomics: Genome-wide analysis of the genetic determinants of drug efficacy and toxicity.،What is pharmacogenomics? Pharmacogenomics is the study of how genes affect a person's response to drugs. The field of pharmacogenomics is still in its infancy. In the future, pharmacogenomics will allow the development of tailored drugs to treat a wide range of health problems, including cardiovascular disease, Alzheimer disease, cancer, HIV/AIDS, and asthma. What about pharmacogenomics?
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