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شیمی::
فارماکوکینتیک (سینتیک دارویی)
Pharmacokinetic properties include:
During the last two decades, there has been a steady improvement in the physicochemical, biopharmaceutical, and/or pharmacokinetic properties of pharmacologically active compounds by the implementa- tion of a prodrug strategy.
Most prodrugs in clinical use are of this type, and they were developed to improve the pharmaceutical and/or pharmacokinetic properties of an active agent, be it a lead candidate, a lead compound, a clinical candidate, a drug candidate, or a marketed drug.
A significant variation is seen in order to improve or eliminate drawbacks related to physicochemical properties which determine the pharmacokinetic behavior, and pharmaceutical and biological performance of already existing drugs.
Drug metabolism pharmacokinetic research has helped to develop drugs with suitable properties.
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